that it doesn't affect them, because if it did, they would watch/listen to pretty much nothing. Damn liberal Hollywood!
I would like to say that it doesn't bother me, but it's always kind of floating in the back of my head. I won't purposefully avoid watching anything because it features conservatives though.
I think it's interesting that most shows that are specifically tailored to conservatives generally suck, while shows that are very liberal tend to be well received. I'm not just talking about The Daily Show vs. Half Hour News Hour either. It works with dramas and pretty much all kinds of media.
All of that said, the reason I didn't watch Frasier is because it wasn't funny. Standard shitty sitcom jokes peppered with the occasional literary reference (or something similarly "intellectual").